In this article, we’ll take an all-out in-depth look at the best vitamin B12 supplements of 2019. And we’ll do this in three steps.
First, we’ll establish and identify guidelines that a supplement must meet. Then we’ll define why is it that way and why it’s essential. And lastly, we’ll evaluate them and put them into a list depending on how they compare to each other.
Vegetarians and Vegans also won’t be cut out – we’ll also take a look at the best vitamin B12 supplements for them specifically.
But above all, I’ll strive to make this as thorough and simple to use of a guide as possible. My one ask would be, if you find any section (chapter) of this article beneficial or helpful, please leave us a comment below. Even one sentence helps and will be highly appreciated.
But for now, let’s dive right in.
During the research process for this article, I went over every single supplement that I could possibly find that primarily contained vitamin B12. Also, many various bestseller lists were examined. Ultimately, all for a well over 250 different supplement evaluation, assessment, and examination.
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Best Vitamin B12 Supplements: What Do They Look Like?
1. Vitamin B12 Amounts
Many will try to say and convince you that the amount of 100% Daily Value (DV) or Nutrient Reference Values (NRV) – depending on where you live – is enough for good health.
Or to put it in other words, they’re saying that 2.4-2.5 micrograms of vitamin B12 daily are what you need for good health. However, this is not true at all. These amounts define how much you need of a nutrient to avoid disease [R, R, R, R].
Needless to say that avoiding disease and having peak performance are two entirely different things. The truth is that you will need much, much more of B12 if you want to have optimal health and peak performance [R, R, R].
Prime Daily Values state that you need between 500 and 1000 micrograms of B12 daily to function at your absolute best. So, this is also precisely what one should aim for.
Furthermore, studies have shown this amount to be completely safe for long-term intake and use [R, R, R, R]. In this regard, for more information see below the chapter on B12 Supplement Interactions With Other Supplements.
2. Vitamin B12 Form
And then there’s also Adenosylcobalamin. Although it’s one of the bioavailable forms (forms that our body does not need to convert to use), it’s very uncommon in supplements. Generally, because it’s a very unstable form [R, R, R, R].
From the three I mentioned before, Cyanocobalamin is the synthetic form.
Although, it’s pretty good at curing deficiencies, when converting to usable forms it releases cyanide molecule. Which basically needs to be detoxified, so energy must be expended to remove it [R, R, R, R, R, R].
It’s incredibly cheap to produce. And many try to advocate that it’s the most beneficial form (this is especially in regards to those manufacturer’s, which use it in their supplements). However, that’s not true at all [R, R, R, R, R].
Then there’s Hydroxocobalamin, which many believe is the best form for vitamin B12. This is because it’s one of the most common vitamin B12 forms that can be found in food naturally. And also our bodies convert it both into Methylcobalamin and Adenosylcobalamin – both of which are the bioavailable forms of the B12 vitamin [R, R, R].
And sure, while it does offer some quite extraordinarily beneficial effects that other forms don’t – for some it can turn out to be quite useless. Because of probable difficulties converting it properly, which is reliant on many factors, especially digestive health. Surprisingly this problem is more common than you might think [R, R, R].
Lastly, there’s Methylcobalamin, which is praised by many.
It’s available to our bodies for use immediately after consumption. It plays a vital role in detoxification. And it does loads of other cool stuff. Furthermore, Methylcobalamin is also the form of the vitamin that babies acquire most of any other cobalamins through mother’s milk [R, R, R, R, R, R, R, R].
So, the best vitamin B12 supplements 2019 should have Methylcobalamin as their primary B12 form. Then if it’s possible any traces of Adenosylcobalamin are also welcome. And so are also traces of Hydroxocobalamin for that added extra benefit.
As for Cyanocobalamin, it’s not necessarily bad – it can still provide a significant benefit if used in appropriate amounts. It is, however, supposedly the least valuable form of these four.
It’s worth mentioning that there is also other forms of vitamin B12 in existence, like Chlorocobalamin, Nitrocobalamin, as well as many others. Yet these are virtually impossible to come across in supplements.
3. Additives In The Supplement
Many assume out of ignorance that additives do not matter, that only thing that matters is the active ingredient (in this case it’s vitamin B12). However, it’s not like that at all.
Having harmful additives in your supplements promises to be not only taxing on the body but are also likely to cause serious side effects. Which more often than not will occur in long-term, however, at times can also be experienced in short-term use.
On the other hand, though, harmless additives are nothing like that and do none of that. Yet, the possibility of some minor side effects (mostly because of some allergies) for select few people can’t be disregarded entirely.
Therefore, ultimately additives make a huge difference between a good and a bad supplement, as well as all the difference between an awesome one and a terrible one.
Thus, as for the best vitamin B12 supplements 2019 – harmful additives must not be a part of them.
4. Quality And Manufacturing Practices
Quality and manufacturing practices used in supplement production is something that isn’t really put on the supplement label.
They’re rather something that is not immediately apparent.
However, they’re extremely important.
Low-quality vitamin B12 supplements can offer quite an unpredictable variety of side effects, because of various impurities that may happen during manufacturing.
Therefore, it’s critical to choose as high-quality supplements as possible.
5. Other Nutrients And Substances Within The B12 Supplement
In vitamin B12 supplements we surely aren’t as concerned with other beneficial substances as we were when evaluating the best multivitamin supplements for 2019.
However, if everything else is more or less the same, supplements that offer some additional beneficial substances or nutrients should be valued higher.
But it’s essential not to go crazy with this because then we’re losing the whole purpose of this list.
Ultimately, vitamin B12 still should be the primary vitamin in the supplement. One or two, or maybe three other substances within it are okay, but everything else beyond that – is deviating too far away from the main thing. Which is B12.
So, in the end, this is kind of the least impactful aspects when finding and evaluating the best vitamin B12 supplements for 2019.
6. Price For The Supplement
Price surely is something that also must be taken into account.
Great vitamin B12 supplements at times can also be overpriced, yet that’s not common at all. In fact, often times the poor quality ones are those that are not a good bang for your buck.
In essence, you are wasting money by buying those.
21 Best Vitamin B12 Supplements 2019 – The List
No. 1 | Thorne Research Methylcobalamin
Thorne Research is probably the highest quality supplement manufacturer out there.
They fulfill and exceed many of the quality standards set, like the impossible TGA and the well-known NSF and cGMP. They are also the only supplement company to collaborate with the universally known Mayo Clinic.
They do some insane amounts of testing for contaminants to make sure that the ingredients are pure. Therefore, the ingredients they use are some of the best, safest and most beneficial for supplements.
To sum it up, it’s actually plainly stupid, how much care they put into quality.
And you can rest assured that in regards to Thorne Research Methylcobalamin it is no different.
This supplement is like the perfect option for your B12 needs and all that comes with the benefits of B12. It offers 1000 micrograms of vitamin B12. Which is precisely what is needed in regards to Prime Daily Values.
All those 1000 micrograms come in the form that is regarded as the most beneficial for B12 (Methylcobalamin). Furthermore, there are no harmful additives within the supplement.
Some may see it as a flaw to not have any other substances within this supplement other than the B12. However, this is a list for supplements of B12 primarily; therefore, it isn’t really a flaw.
However, there is also the Thorne Research, B-Complex #12, which is the number five on this list and offers less B12 but has a bunch of other B vitamins additionally.
As for the price of Thorne Research Methylcobalamin, for what it offers – it’s an insane deal.
Or to put it in perspective – it is 18.00$ for a 60 day supply, which is 0.30$ a day.
No. 2 | MegaFood Methyl B12
MegaFood position themselves and are known in the market for being the high-quality whole food supplement manufacturer. And in that, they are incredibly real and honest about the process.
They are working with farmers and producing their supplements directly from food. They’re also being extremely transparent into everything that they do, and this is to a point where you can watch the manufacturing process online 24/7
MegaFood Methyl B12 offers 500 micrograms of vitamin B12 in the form of Methylcobalamin. Furthermore, it also contains only harmless additives. However, that’s not all.
Therefore, this supplement is not only viable in increasing your B12 levels, but also improving the fundamental process of methylation as a whole. This is because it offers all three vitamins that are irreplaceable to make this process happen.((Hyman M (Dr.) The Ultramind Solution. New York: Scribner, 2010, p. 124-133.))
On top of that MegaFood Methyl B12 also has Beet Root.
Beetroot is known to reduce cholesterol, lower blood pressure, boost physical performance, helps maintain a healthy weight and has other benefits. Additionally, it is also a good source of various minerals, as well as vitamin B9 and C [R, R, R, R, R].
As for the price – it’s slightly more expensive than the Thorne Research Methylcobalamin. Or to be exact, it’s 29.20$ for a 90 day supply, which is approximately 0.32$ a day.
No. 3 | Garden of Life Vitamin Code Raw B-12
Here’s yet another whole food vitamin B12 source, which is invigorated by many various certifications.
Garden of Life is USDA Organic, Non-GMO Verified, Certified Gluten Free, has certain NSF certifications as well as many others, which overall seem to make it a pretty high-quality brand.
Garden of Life Vitamin Code Raw B-12 is a supplement that contains 1000 micrograms of Methylcobalamin, offers other beneficial substances and has only completely harmless additives.
Raw Probiotic & Enzyme Blend has the potential of improving your gut health, which is so incredibly important in the vitamin B12 absorption. Probiotics are also known to have other valuable benefits [R, R, R, R, R, R].
It also offers Raw Organic Fruit & Vegetable Blend that is a composition of 23 various fruits and vegetables, all of which are of organic sources.
This provides incredible amounts of valuable dietary fiber, as well as all kinds of nutrients and possible benefits connected to the individual fruits and vegetables [R].
As for the price, it is slightly more expensive than the two supplements, which came before it. It costs 11.89$ for a 30 day supply, which is approximately 0.40$ a day.
No. 4 | Vegansafe B-12
The supplement is manufactured by the Global Healing Center, a widely recognized source for natural health information.
On top of that, it is a member of the Organic Trade Association and is trusted by the Organic Consumers Association, APHA, and CBCN.
USDA Organic is also something that they are known for.
Vegansafe B-12 offers 2500 micrograms, of which 80% is Methylcobalamin, and 20% is Adenosylcobalamin. Or to be precise – it provides 2000 micrograms of Methylcobalamin and 500 micrograms of Adenosylcobalamin.
Both are the bioavailable forms of the vitamin B12, and in that, they’re the most beneficial.
In fact, Global Healing Center believes so much in it’s product that if you get it through their website they offer 180-Day Money Back Guarantee.((I’m not really sure if this guarantee works with other distributors as well, however, I seriously doubt that.)) This means that if at any point you’re not 100% satisfied with the product, you can get not only a full refund within 6 months but also all of the return shipping costs paid for you.
Which is pretty insane and gives a little better idea of how good this product actually is.
However, I do believe that if you’re not vitamin B12 deficient or your body isn’t struggling with B12 absorption, 2500 micrograms a day might be too much.
So, if you really want a good B12 punch – definitely give it a try. It just might become your best ally in truly rising your energy levels.
On this same token, it’s probably also best to just go straight ahead and get it from Global Healing Center as that will ensure the 6 months satisfaction guarantee.
To end off, few words about the price. To no surprise, the high amounts of both bioavailable forms, as well as only harmless additives, do not exactly come cheap. It prices at 29.95$ for 30 (servings) days, which is approximately a dollar per serving (day).
No. 5 | Thorne Research B-Complex #12
As for the brand itself, I did already go over of how insanely good the quality is. If you somehow slipped it by, go back to the No. 1 supplement on this list.
Similarly as Vegansafe B-12 also Thorne Research B-Complex #12 offers both bioavailable forms of vitamin B12 – Adenosylcobalamin and Methylcobalamin.
The only difference is that the latter offers them in much more reasonable amounts.
Or in other words, the Thorne Research B-Complex #12 offers 600 micrograms of vitamin B12 – 50% or 300 micrograms of that are Adenosylcobalamin, and the other 50% or 300 micrograms are Methylcobalamin.
However, that’s not even close when considering all the nutrients that this supplement has. It also offers a bunch of other B vitamins, as well as Choline.
Here’s all that it additionally offers besides the 600 micrograms of vitamin B12:
- Vitamin B1 – 40 mg,
- Vitamin B2 – 28.6 mg,
- Vitamin B3 – 80 mg,
- Vitamin B5 – 45 mg,
- Vitamin B6 – 23.4 mg,
- Vitamin B7 – 80 mcg,
- Vitamin B9 – 668 mcg,
- Choline – 14 mg.
The forms that those vitamins are in are not always the most effective ones; however, they will be of considerable benefit nonetheless.
On top of that, of course, you’re also getting only harmless additives within the Thorne Research B-Complex #12.
In regards to the price, I already mentioned that it’s the most value for money on this list. You get the two forms of B12 plus everything that I listed for 17.00$ for 60 days, which is 0.28$ a day.
No. 6 | Garden of Life MyKind Organics B-12 Organic Spray
Garden of Life MyKind Organics B-12 Organic Spray, as the name suggests and similarly as the Vegansafe B-12, is a spray for all of you who would rather not take pills.
This spray offers 500 micrograms of Methylcobalamin, as well as 2 milligrams of their Certified Organic Food Blend. Which essentially is all kinds of organic fruits and vegetables stuffed together.
And being such this organic blend provides dietary fiber along with all of its benefits, like eliminating toxins from the body, reducing the risk of cancer, improving gut health, promoting weight loss and other benefits [R, R, R, R, R, R].
Certainly, the fruits and vegetables within the blend will also provide with most of all the vitamins and minerals that such products would naturally have. The blend contains these fruits and vegetables (22 in total):
Organic Beet (root), Organic Carrot (root), Organic Spinach (leaf), Organic Broccoli (flower & stem), Organic Tomato (fruit), Organic Kale (leaf), Organic Red Cabbage (leaf), Organic Parsley (leaf), Organic Brussels Sprout (leaf), Organic Green Bell Pepper (fruit), Organic Cucumber (gourd), Organic Celery (stalk), Organic Garlic (bulb), Organic Ginger (root), Organic Green Onion (root), Organic Cauliflower (flower & stem), Organic Asparagus (flower & stem), Organic Strawberry (fruit), Organic Cherry (fruit), Organic Blackberry (fruit), Organic Blueberry (fruit), Organic Raspberry (fruit).
As for the additives, overall it looks good and harmless. However, there is some flavoring involved. Meaning, the Garden of Life MyKind Organics B-12 Organic Spray uses organic raspberry flavoring.
Although superficially it could be deemed harmless (because of the name ‘organic’), that may also not be the case. This is because flavorings as such may contain so-called “incidental additives” that are not required to be shown on the label, as well as it may be contaminated with something additionally during the manufacturing process [R, R, R, R, R].
While this may not be the case, such possibility generally can’t be completely ruled out. However, as towards Garden of Life MyKind Organics B-12 Organic Spray, it can.
Labdoor has tested this supplement and rated its purity at 100%. Consequently, it should be good in this regard.
The best part about this supplement is that you can easily increase the intake by just consuming more sprays daily. So, one spray contains those 500 micrograms of B12 and 2 milligrams of that Certified Organic Food Blend. But two sprays will provide 1000 micrograms of B12 and 4 milligrams of the blend.
It is indicated that one supplement will contain approximately 140 sprays. Which depending on how much you’d like to go for 500 or 1000 micrograms a day is either for 140 or 70 days.
Similarly, if we evaluate the costs, it would mean 0.09$ (140 day supply) or 0.18$ (70 day supply) a day as the supplement’s original price is 12.59$. And overall this makes it one of the cheapest options on this list.
No. 7 | Fairhaven Health MotilityBoost for Men
Yeah, yeah, I know what you’re thinking – “Matiss, WHAT IS THIS?”
But hear me out.
Let’s take a step back and look at the supplement for what it really is and not for what it’s marketed for. So, what are the nutrients and other beneficial substances that this supplement provides?
Well, first it offers 500 micrograms of Methylcobalamin. Which is the form of vitamin B12 that we exactly want.
Then there’s also 25 milligrams of vitamin B6, which contains both pyridoxal-5-phosphate and pyridoxine HCl at the distribution of 50/50. The former of both forms is the most effective form for B6, but the latter is kind of a standard form for B6 used in supplements [R, R, R, R].
Finally, there’s also the 1455 milligrams of Proprietary Blend. This blend contains N-Acetyl L-Cysteine, L-Arginine, Quercetin, L-Carnitine (as L-carnitine L-tartrate), Mucuna Pruriens (seed) Extract (standardized to 40% L-Dopa), CoQ10.
All of the blend ingredients are not only beneficial for what it’s marketed for. In fact, they will be much of a benefit to anyone who decides to consume them, even women. So, the Fairhaven Health MotilityBoost for Men is much much more than just a sperm quality increasing supplement.
As for the price, it costs 17.32$ for a supply or 30 days, which is approximately 0.58$ a day.
No. 8 | Pure Encapsulations B12 Folate
Pure Encapsulations is a supplement manufacturer of among the highest of quality. They are NSF and GMP certified. They also exceed the quality standards set by USP, as well as they partner with various Universities and health care professionals.
On top of all that, their supplements and the raw materials that those are made of get tested by a number of independent third-party laboratories.
Pure Encapsulations B12 Folate combines within itself 800 micrograms of Methylcobalamin and 800 micrograms of the most effective form of vitamin B9 (Folate). Thus, it’s the perfect choice for anyone who seeks to combine within a single supplement the best of the two vitamins [R, R].
The supplement has only harmless additives that will not harm your health even if you would use it daily for the rest of your life.
It prices at 16.40$ for a supply of 60 days, which is 0.27$ a day.
No. 9 | Vital Nutrients Vitamin B12 (Plus Option With MethylFolate)
The only nutrient that the Vital Nutrients Vitamin B12 contains is vitamin B12. So, it does not offer any additions – quite like the Thorne Research Methylcobalamin does.
Vital Nutrients is a company that makes supplement quality their top priority. There isn’t, however, much information other than their own claims to affirm this.
The supplement itself contains 1000 micrograms of Methylcobalamin. Its additives are Rice Powder, Vegetable Cellulose Capsule and Silica. All of these are completely harmless and safe to have in the supplement.
As for the price, it costs 22.20$ for a supply of 100 days, which is about 0.22$ a day. Definitely a good option.
This variation contains all the same ingredients with the exception of Ascorbyl Palmitate (harmless additive) but comes with an addition of Folate (vitamin B9). To be exact, with an addition of the best form of Folate [R, R].
It prices at 25.40$ for a supply of 100 days, which is approximately 0.25 a day.
Without a doubt, it’s definitely worth the extra money over the version without the Methylfolate within it.
No. 10 | Garden of Life Vitamin Code RAW Iron
This particular supplement – the Garden of Life Vitamin Code RAW Iron – is not for everyone.
“What do you mean with “not for everyone,” Matiss?”
Well, I mean precisely that. This supplement should only be consumed by menstruating women. Depending on their diet vegetarians and vegans may also use it, however, primarily it’s for menstruating women only.
This is because the supplement in addition to the B12 that it has also contains high amounts of Iron. And Iron can be extremely detrimental if it gets overdosed. Furthermore, generally, its supplementation is not needed [R, R, R, R, R, R, R, R].
To be more precise, the Garden of Life Vitamin Code RAW Iron contains 500 micrograms of Methylcobalamin, 22 milligrams of Iron, 25 milligrams of vitamin C, 400 micrograms of Vitamin B9, as well as 60 milligrams of the RAW Probiotic & Enzyme Blend and 310 milligrams of RAW Organic Fruit & Vegetable Blend.
As for the Vitamin C and Vitamin B9 forms – they aren’t indicated. So, it’s pretty sure to assume the worst. Vitamin C, even when strictly synthetic has shown to be effective. On the other hand, the synthetic form of Vitamin B9 is quite useless and ultimately won’t provide much of a benefit [R, R, R, R, R].
As for the RAW Probiotic & Enzyme Blend and RAW Organic Fruit & Vegetable Blend, it’s the same that we had in the Garden of Life Vitamin Code Raw B-12. The only difference is that here’s more of it.
But above all, remember – this one is for women in their reproductive age.
As for the cost, Garden of Life Vitamin Code RAW Iron is 11.89$ for a supply of 30 days, which is approximately 0.40$ a day.
No. 11 | Nature’s Plus Vitamin B-12 (2000 mcg)
Nature’s Plus as a manufacturer claims to be and have the Unmatched 45-year History as a Trusted Manufacturer & Supplier of Natural Vitamins and Nutritional Supplements.
While I honestly doubt it’s as unmatched as they claim it to be, one thing’s for sure.
They go pretty hard on natural and organic.
Nature’s Plus Vitamin B-12 (2000 mcg), as it is evident from its name, offers 2000 micrograms of vitamin B12. This B12, similarly as most supplements on this list, comes in the form of Methylcobalamin.
This supplement also does not mess with any additional substances to that B12. But it messes quite a bit with various additives as there are many of those. Nonetheless, all of them still are harmless and okay for long-term use.
As for pricing, Nature’s Plus Vitamin B-12 (2000 mcg) is 18.49$ for 60 day supply, which is 0.31$ a day.
No. 12 | Pure Encapsulations Adenosyl/Hydroxy B12
It will, however, throw at you the Adenosylcobalamin and Hydroxycobalamin.
Many will try to tell you that both of these forms are quite hard to stabilize within supplements. Others will try to convince you that having these both forms is impossible and the manufacturer must be misleading consumers.
Pure Encapsulations as a manufacturer, however, is nothing of that. They are one of the highest quality supplement manufacturers out there. So, there is no doubt that if they promise to deliver – they will indeed deliver.
Pure Encapsulations Adenosyl/Hydroxy B12 contains in total 2000 micrograms of Vitamin B12. This amount is divided equally among the B12 forms of Adenosylcobalamin and Hydroxycobalamin – 1000 micrograms for each.
Also, the additives are some of the safest and without-doubt harmless additives out there.
Some may see it as a big turn-off not having Methylcobalamin, but I don’t see it that way. I instead see it as quite an unconventional option for all your B12 needs. Furthermore, it’s a great addition to any daily primarily Methylcobalamin supplement to take every once in a while.
As for the price, it costs 21.50$ for a supply of 90 days, which is approximately 0.24$.
No. 13 | Nature’s Plus Source of Life Garden Organic Vitamin B12
This is a supplement that would deserve to be much higher on this list (placed as No. 6). However, it does have a slight hiccup in its additives; therefore, it’s placed No. 12.
In truth – it’s the first with any kind of hiccups in regards to additives.
This slight drawback that I’m talking about is Organic Rice Maltodextrin.
“But it is organic, right? So, why is it a problem???”
Well, organic doesn’t always mean or equals healthy. Especially that is when it comes to various forms of sugar. And Maltodextrin is one of those.
It may seem that, if it’s made out of organic sources, it should be good for you, but this illusion is precisely what many manufacturers are counting on. Sure, overall the organic sugar will be less contaminated than the regular sugar, but this is of little importance as it’s still linked to the same devastating adverse effects as any form of sugar [R, R, R, R, R, R, R].
On top of that being a Maltodextrin it can cause such side effects as a sudden headache, itching, rash, difficulty breathing, bloating, diarrhea, increase susceptibility to various diseases, as well as have a list of many other adverse effects [R, R, R, R, R, R].
Of course, this is not something that will happen for each and every single one of us, if we were to use it, but it’s worth noting nonetheless.
On the flip-side though, this is the only negative thing about the supplement. And as of itself Nature’s Plus Source of Life Garden Organic Vitamin B12 is a good one, that’s for sure.
It offers 1000 micrograms of Methylcobalamin and 450 milligrams of Certified Organic Whole Food Blend, which consists of many various organic fruits and plants.
Additionally, it also provides insignificant amounts of vitamin B1, B2, B3, B5, B6, B7, and B9 made out of organic sources.
Besides the already discussed additive, the rest of them are completely harmless and okay to consume daily.
As for the price, it is relatively more expensive than the rest. However, overall doesn’t come with a hefty price tag, despite it being fully organic.
It costs 15.09$ for a 30 day supply, which is approximately 0.50$ a day.
No. 14 | Doctor’s Best Fully Active B12 (1500 mcg)
Doctor’s Best positions itself in the market as the Science-Based Nutrition manufacturer.
They claim to make supplements primarily with branded ingredients that are thoroughly researched, manufactured to the highest quality standards (only in cGMP-certified facilities), and rigorously tested every step of the way.
No third party assertions, however.
Doctor’s Best Fully Active B12 (1500 micrograms), as it’s evident from the name, offers 1500 micrograms of vitamin B12. The B12 is in the form of Methylcobalamin.
As for additives, they should be all good, meaning, harmless for long-term use. But there is, however, an aspect that this supplement particularly shines in regards to.
And that is the price. It costs 5.07$ for 60 day supply, which is approximately 0.08$ a day. That is insanely cheap for what it offers. This is without a doubt the most affordable supplement on this list.
While it’s incredibly cheap, at the same time much like any other supplement before it on this list – it is a Non-GMO. On top of that, it’s also Gluten Free and suitable for vegans.
No. 15 | Live Wise Naturals B12
This one’s in the form of a liquid, and it offers the most significant supply of B12 within a single product (container).
Live Wise Naturals is a manufacturer with a passion for pure, healthy and effective ingredients that have passed clinical trials.
Supposedly before they sell any of their supplements, they test them first both by themselves and by their trusted circle of experts, friends, and family.
Although there are no third party assertions, they offer an unconditional 365 day 100% money back guarantee, which truly conveys that they do believe in their products to be worthwhile.
Live Wise Naturals B12, as I already mentioned earlier, is a liquid form supplement containing 1000 micrograms of B12 in the form of Methylcobalamin.
As for additives it uses purified water and organic grape alcohol. Although both shouldn’t impose any health risks, there are people, who do not want to use any type of alcohol. This is also, why it’s not higher on this list.
The remarkable thing about the Live Wise Naturals B12 is that it’s extremely easy to alter and customize the dose you’re taking. One drop equals 200 micrograms of B12. For 1000 micrograms you have to do 5 drops.
In regards to price, if you were to take 1000 micrograms a day, it will be able to supply you for 180 days (6 months). This is at the cost of 19.99$, which is 0.11$ a day.
No. 16 | Life Extension BioActive Folate & Vitamin B12
Life Extension claims to be the best quality-for-money type of manufacturer. They claim to put all their focus on quality, purity, and potency.
They produce their supplements in GMP-certified facilities and give them a full one-year return policy (100% satisfaction guarantee).
On top of that, they are the three-time No. 1 Catalog/Internet Merchant as rated by ConsumerLab.com.
Life Extension BioActive Folate & Vitamin B12 is a supplement that offers both folate (vitamin B9) and cobalamin (vitamin B12) – both in their most effective forms, respectively – L-5-Methyltetrahydrofolate and Methylcobalamin [R, R, R, R].
Both of these come in moderate amounts. The vitamin B12 you’ll find in quantities of 300 micrograms. Plus, there will be the vitamin B9 in amounts of 400 micrograms. The supplement does not offer any other nutritional substances.
As for the additives – they are completely harmless and safe to use long-term.
Life Extension BioActive Folate & Vitamin B12 costs 9.00$ for a supply of 90 days. That equals 0.10$ a day.
No. 17 | Bluebonnet Nutrition EarthSweet Chewables Methylcobalamin
Bluebonnet Nutrition is THE supplement brand if you ever want your vitamins to be tasty. USDA Organic, KOF-K Kosher Certified, GMP, and NSF Certified – all are their decorations.
On top of that, it is the 3-time-winner of Natural Choice Awards (2016-2018), as well as the winner of many other various contests for supplements.
And the list of such awards is a pretty long one.
The Bluebonnet Nutrition EarthSweet Chewables Methylcobalamin offers 1000 micrograms of Methylcobalamin along with various flavoring and taste-enhancing additives.
Such as natural raspberry flavor, natural strawberry flavor and Earthsweet [juice concentrates (wild blueberry, cranberry, prune, cherry, strawberry, grape, raspberry and bilberry fruits, grape seed and raspberry seed extracts), cane crystals].
Although these flavorings may seem harmless, in truth, they may not be. Just because a flavoring is of natural or organic sources does not necessarily indicate that they are safe to consume and harmless. In fact, many times it can be the exact opposite [R, R, R, R, R].
As a general rule of thumb, it’s better to use and consume supplements that are not manufactured with all kinds of or even just one flavoring.
It’s just a safer way how to avoid unnecessary toxins and contaminants that might be incidentally present due to the manufacturing process.
This, however, is something that I believe is of little relevance to Bluebonnet Nutrition in general and the EarthSweet Chewables Methylcobalamin.
Their certifications and award-winning streak pretty much approve that.
As for all the other additives that it has – they’re all good.
It prices at 7.96$ for a supply of 60 days, which is about 0.13$ a day. Which in truth is truly cheap considering the origins of the ingredients that it employs.
No. 18 | Go Nutrients Vitamin B12 (Methylcobalamin)
Here are another one of B12 supplements that contain flavoring. Which in this case is an organic one.
Go Nutrients is a liquid form, alcohol-free various supplement manufacturer. In this regard, NSF and GMP is something that is attributed to their name.
But on top of that, they are so confident in their products that they also provide a 90-day no-questions-asked money-back guarantee.
Meaning, you can order one of their products, use it for 30 days and then decide, if it fits you. If it does, then all good. If it doesn’t, then you’ll just send it back. And you get your money back. Risk-Free.
Go Nutrients Vitamin B12 (Methylcobalamin) offers 3000 micrograms of Methylcobalamin, which may seem a lot because it exceeds the recommended 1000 micrograms a day three times. However, the dose of the supplement can be easily reduced to approximately 1000 micrograms.
Meaning, it’s claimed that 1/4 of a teaspoon, which is about 20-30 drops contains 3000 micrograms of the active B12. So, to reduce the dose to 1000 micrograms just take 3 times fewer drops, which would be anywhere between 7-10 drops a day.
As for the additives, it’s all good but one ingredient. In regards to that, I’m not saying that in this supplement specifically, it might be a problem, I just want to make you aware that it could be.
So, the potentially problematic additive is the Organic Raspberry Flavoring.
Again, just because something’s organic, does not necessarily mean that it is healthy and harmless. In fact, many times there is nothing harmless about any type of flavoring – be it the ordinary one, the natural one, or organic one [R, R, R, R, R].
Consequently, although the possibility of taking into account that their NSF and GMP certified is low, the probability still exists. And this is also why it’s lower on the list than it could have been.
Ultimately, if you decide on this one, it’s probably best to buy this straight from the Go Nutrients website as then you are definitely eligible for that 90-day guarantee just in case.
At their website, the Go Nutrients Vitamin B12 (Methylcobalamin) costs 21.95$ for 48 servings of 3000 micrograms of B12, which would be about 0.46$. However, if you use the dose of 1000 micrograms, it will be 21.95$ for 144 servings, which is approximately 0.15$ a day.
No. 19 | Natural Factors B12 Methylcobalamin
Natural Factors is a manufacturer, which encompasses the whole process. They start by growing the raw materials on their certified-organic farmland and fulfill every single action and step in between till the end product – the supplement.
Their products are certified by ISURA, which approves that the ingredients that Natural Factors use are non-GMO, pure and potent.
But their farms, manufacturing processes, care, and other endeavors will leave you in awe.
Natural Factors B12 Methylcobalamin offers 1000 micrograms of Methylcobalamin. It does not offer any other nutritional substances.
As for additives, they might be safe to use for most people. However, I am not a fan of the lactose they are using from milk. This is because dairy products are one of the two most widely spread hidden allergens that there is. They lead to brain problems.
They are referred to as hidden because the symptoms of those may develop at any time in the time frame of 3 days after the consumption, which makes them extremely hard to become aware of. So, essentially you might even have one without being aware of it.((Hyman M (Dr.) The Ultramind Solution. New York: Scribner, 2010, p. 295–297.))
The devastating truth is that such allergy does not end with causing inflammation and toxic effects on your body. It can be the root factor of various conditions starting from simple brain fog to ADHD, depression, dementia and autism and other chronic diseases.((Hyman M (Dr.) The Ultramind Solution. New York: Scribner, 2010, p. 295–297.))
Therefore, this should be a supplement only for those, who actually know that they don’t have such hidden allergies. If you don’t know for sure or haven’t ever really paid attention to that, any other B12 supplement on this list before this one will be a much, much better choice.
As for the price of this one, it prices at 10.47$ for a supply of 90 days, which equals approximately 0.12$ a day.
No. 20 | Superior Source Methylcobalamin B-12
Superior Source position themselves in the market as the creators of soft-molded instant release vitamins. They produce their supplements in GMP certified facilities.
But other than that, there’s no third party assertions or anything else other than their own claims about themselves.
As I already mentioned, this supplement offers Methylcobalamin and has no other nutritional substances to it. The amounts of the B12 form are 1000 micrograms.
As for additives, having Lactose is not that good as we already discussed looking at the No. 18 of this list.
The massive downside of this brand and therefore also the supplement is that it pretty much offers no information as to how high of a quality the supplement actually is. Supposedly the quality should be good from the information given on their website. But it’s quite a guess.
If you choose to go for this one, it costs 10.50$ for a supply of 60 days, which is about 0.18$ a day.
No. 21 | GNC Vitamin B-12 (1000 mcg)
GNC Vitamin B12 is, however, slightly more different than other supplements that are on this list. It offers 1000 micrograms of Cyanocobalamin.
Yes, I didn’t misspell it – Cyanocobalamin. Not Methylcobalamin. Not Adenosylcobalamin or Hydroxycobalamin. But Cyanocobalamin.
“Wasn’t that the least desirable form?” – Yes, it was.
Basically and essentially I chose to put this supplement here to let you know that you shouldn’t completely avoid Cyanocobalamin. Prefer the other forms, but do not run from this one like the plague.
Because it is not that at all.
Therefore, if you do ever encounter Cyanocobalamin in a multivitamin supplement or any other supplement that you originally chose not for the B12 it had, this somewhat flawed form of B12 is definitely not the cornerstone deciding factor to refuse the consumption of such supplement.
Having Cyanocobalamin is way, way, way better and beneficial for your health than having no B12 vitamin at all.
Just keep that in mind. Especially, when choosing supplements or going for ones that are not primarily meant for B12.
3 Best Vitamin B12 Supplements For Vegetarians 2019
Similarly as with vegans, also for vegetarians, it can be a challenge to find appropriate supplements.
Although the list of 21 best vitamin B12 supplements 2019 above has some vegetarian supplements among them, they are more to the bottom of the list.
There is, however, good news.
Many of the supplements that are near the top of the list are actually vegan, so those are something that can easily be consumed also by vegetarians.
For this purpose, it’s not really useful to go more into detail here about which exact supplements of B12 are the best for vegetarians. Because the top 3 lists of supplements for vegetarians and vegans will be precisely the same.
So, let’s get right into the list of 3 best vitamin B12 supplements for vegans.
3 Best Vitamin B12 Supplements For Vegans 2019
In regards to some vitamin supplements, it’s tough to find and identify supplements that are vegan-friendly.
The vitamin B12 supplements, however, are not that case.
In fact, most of the supplements on the list of 21 best vitamin B12 supplements 2019 above are vegan. So, here we’ll briefly go over the 3 best vitamin B12 supplements for Vegans (and Vegetarians).
This list will be geared more towards assuring that those particular supplements are in fact vegan. But you may catch me repeating myself as I will still provide the most essential information on the supplement.
For a full view on any of these supplements, be sure to go back to the list of 21 best vitamin B12 supplements 2019 above. This, of course, in case you missed it or jumped straight to this section.
Vegan No. 1 | MegaFood Methyl B12
MegaFood Methyl B12 is a supplement that is certified by Vegan Action.
Vegan Action is a non-profit organisation working to eliminate all animal suffering, to reduce environmental impacts and to improve human health through a vegan diet. They’re devoted to creating a happier, healthier, and greener world for all.
Their certification is one of the most recognized certifications for vegan products. So, if it’s on a supplement, it’s vegan alright.
MegaFood Methyl B12 is a supplement that offers 500 micrograms of Methylcobalamin, 340 micrograms of L-5-MTHF (vitamin B9), 8 milligrams of Pyridoxal-5-Phosphate (vitamin B6) and 225 milligrams of Beet Root.
This supplement has only harmless additives.
It is also NSF-certified Gluten Free, Pesticides & Herbicides Tested Free, Soy Free, Dairy Free, Non-GMO, Kosher and Glyphosate Residue Free.
It prices at 29.20$ for a 90 day supply, which is approximately 0.32$ a day.
For more information on the MegaFood Methyl B12 see above the No. 2 of the 21 best vitamin B12 supplements 2019. Or click below.
Vegan No. 2 | Garden of Life Vitamin Code Raw B-12
Garden of Life Vitamin Code Raw B-12 is also a supplement that is vegan certified by Vegan Action.
This particular supplement offers 1000 micrograms of Methylcobalamin, 60 milligrams of Raw Probiotic & Enzyme Blend, as well as 20 milligrams of Raw Organic Fruit & Vegetable Blend.
Garden of Life Vitamin Code Raw B-12 has only harmless additives.
It is also USDA Organic, Non-GMO Verified, Certified Gluten Free, NSF-certified, Kosher.
It prices at 11.89$ for a supply of 30 days, which is about 0.40$ a day.
For more information on the Garden of Life Vitamin Code Raw B-12 see above the No. 3 of the 21 best vitamin B12 supplements 2019. Or click below.
Vegan No. 3 | Vegansafe B-12
Global Healing Center (the supplement manufacturer) is a widely recognized source for natural health information. Organic Trade Association, Organic Consumers Association, APHA, CBCN, USDA Organic – all are something that can be associated with them.
Therefore, it’s extremely unlikely, in essence, impossible that they would mislead about Vegansafe B-12 being vegan safe.
This particular supplement offers 2500 micrograms of vitamin B12 (80% Methylcobalamin and 20% Adenosylcobalamin). It provides no other nutritional substances.
The additives they use are completely harmless, and therefore, fine to use every day.
It is priced at 29.95$ for a supply of 30 days, which is about a dollar a day. It’s best to get it straight from the Global Healing Center as they offer a 180-Day Money Back Guarantee (6 Months of Guarantee) if you’re not completely happy with the product.
For more information on the Vegansafe B-12 see above the No. 4 of the 21 best vitamin B12 supplements 2019. Or click below.
B12 Supplement Interactions With Other Supplements
General Information On The Interactions
Any B12 supplement generally is a good fit with other supplements, especially the best multivitamin supplements.
But to really identify and be completely sure, if any two supplements that offer B12 are compatible, it comes down to two aspects – Prime Daily Values (PDVs) and Upper Tolerable Intake Levels (ULs).
PDVs aims to identify the actual amounts of various vitamins and other nutritional substances to be taken daily to achieve optimal (the best possible) health.
ULs, on the other hand, aims to identify the maximum daily intake of various vitamins and other nutritional substances that can be taken long-term (life long) without any adverse effects – only the positive ones.
Thus, the combined amounts of B12 in various supplements preferably should be within the range or about the amounts that are defined by PDVs. However, whenever the combined amounts exceed them, you should make sure that they do not exceed the ULs.
The takeaway message in this is that prefer PDVs, but do not exceed ULs. Because if you do, long-term use of such amounts is likely to cause adverse effects, which then undermines the whole purpose of improving your health to the maximum with supplements.
As mentioned before in the article, the PDV of vitamin B12 is 500-1000 micrograms. But something that we haven’t really talked about yet are the ULs.
However, it’s not that straight forward with the ULs for the vitamin B12.
Or, in other words, particularly for vitamin B12 there are no amounts of the substance that are known to affect health adversely.
Therefore, you shouldn’t ever supplement with more than 5000 micrograms daily. But it would be best not even to go that far.
Of course, this does not account to cases, if you’re severely B12 deficient. In those instances use whatever amount of B12 for a certain period your doctor recommends.
Generally, after the deficiency has been cured the dose will be brought down. And then it should be within or about PDVs, but never exceeding ULs to maintain the perfect health.
Examples Of The Interactions
Okay, so to get the better hang of the idea explained in the previous section, let’s look at some examples.
Generally, it could be said that there are only two variations you could get vitamin B12 from other than a B12 specified supplement. The first group is multivitamin supplements, and the other is other supplements (for lack of a better reference).
Example #1 Of Using B12 Supplement
Let’s say you’re using a multivitamin supplement daily (which by the way you should be doing, if you want the best health possible), which offers 100 micrograms of B12 in the form of Cyanocobalamin. This is something extremely common among multivitamin supplements.
So, the question is, would it be okay to use daily the No. 1 of the best B12 supplements 2019 (Thorne Research Methylcobalamin) along with the particular multivitamin supplement?
The answer is Yes, it would be completely fine to use it daily along with that multivitamin supplement.
If we look at the total amounts of B12 within the No. 1 and the multivitamin supplement of this example, we get a 1000 micrograms of Methylcobalamin and 100 micrograms of Cyanocobalamin. That is 1100 micrograms for a grand total.
1100 micrograms of B12 exceed what is defined by PDVs because the combined amount is more than 1000 micrograms. However, it does not exceed the ULs of 5000 micrograms.
Therefore, this amount is completely safe, harmless and ultimately this will be extremely beneficial.
Example #2 Of Using B12 Supplement
Let’s look at one more example.
Let’s say that you’re using a supplement that incidentally (you’re not using it primarily for B12) adds 300 micrograms of Methylcobalamin.
If you, for example, choose that you would like to add the No. 1 of the best B12 supplements 2019 to your regimen, it will result in 1300 micrograms of Methylcobalamin daily.
And this amount although exceeds the amount defined by PDVs, is far from the absolute maximum intake level daily that is defined or can be presumed by ULs – the 5000 micrograms.
On the other hand, if you were to choose the No. 2 of the best B12 supplements 2019, you would get in addition to those 300 micrograms of Methylcobalamin another 500 micrograms of Methylcobalamin.
So, the combined amounts would be 800 micrograms of B12, which is within the range of PDVs. And this is the amount that’s perfectly good to intake daily.
Example #3 Of Using B12 Supplement
Let’s look at yet another quick example.
Let’s say you’re using a multivitamin supplement daily that offers 500 micrograms of vitamin B12. And on top of that, you’d like to add one of the supplements on the list of 26 best vitamin B12 supplements 2019.
However, as your multivitamin supplement already contains 500 micrograms of B12 and that is within the range of PDVs, you don’t really need to add another B12 supplement.
This, nonetheless, is entirely your choice as you might find or feel that adding some more B12 does positively influence your well-being.
In this regard, you can use any one singular supplement on this list of 26 best vitamin B12 supplements 2019.
This is because the combination of one of them daily along with 500 microgram-B12-multivitamin will not ever exceed the 5000 microgram mark defined by ULs.
What If It Doesn’t Work?
So, let’s say you get a supplement from this list, and after use of 4-6 weeks, you’re not feeling any benefit.
There are many reasons, why this could be. Truly many.
One of the most common ones would be that you’re gut health is not in good shape. Meaning, it’s out of shape completely and inflamed.
In this regard, the vital thing to note is that you can’t eat junk food all the time and use supplements as quick fixes to get the necessary nutrients that you need daily. This does not work that way.
Sure, you might experience some improvements, and it would still be better than disregarding supplements completely, but…
There are many substances that we need from foods like vegetables and fruits to achieve the best kind of health that can’t really be supplemented.
In this regard, I must mention that health is a set of many factors, all of which play a significant role in your well-being, mental clarity and performance.
So, what to do about your gut health to improve it?
Well, start eating more fruits and vegetables and other fresh products. Get organic ones where possible. On top of that, you could also add a probiotic supplement, which will help to heal the damaged and inflamed gut (microbiome).
But most importantly start to step by step eliminating (or limiting) junk-food from your everyday diet. And start eating less and less processed foods.
But if you’re not ready to do that at least… At the very, very, very least… Eliminate the two most harmful substances in processed foods from your diet completely. Those two are hydrogenated oils and high-fructose-corn-syrup (for a list of it’s alternative names see the article on Additives).
Another widespread reason why you might not be feeling any benefit or that benefit is diminished is because you’re not getting enough of other vitamins, minerals, and other substances. And it can go hand in hand with the previous one.
You see in our organisms it does not work that way that a single vitamin fulfills and carries out all of the functions that it has the capacity to carry out.
Here’s what I’m trying to say.
There are two ways how the B12 does things when it lands in our organisms, so to say. One – it fulfills and carries out functions that only the B12 can activate within our bodies to be carried out. And two (and this accounts for most cases) – it interacts with other vitamins, minerals, and other substances to carry out and fulfill various functions in the body.
So, in the first case, it’s completely fine to take a singular B12 supplement.
But as regards to the second instance only using a B12 supplement will not be enough. Because you might intake all of the needed B12, but lacking other certain vitamins, minerals and other substances will make this available amount of B12 useless.
Again – because the B12 can’t replace any of the other nutritional substances. And thus, as it can’t be used because of the lack of for example vitamin B6 or B9, it ultimately just gets excreted.
So, to get the most out of any B12 supplement, you should also for the very least use a multivitamin supplement daily.
For other reasons that could make you not feel the benefit of taking a B12 supplement, stay tuned for a future article.
Final Thoughts On The Best B12 Supplements
There is absolutely no doubt that vitamin B12 is an essential vitamin for your well-being and mental performance. Yet, for the best health, it’s not abundant enough in nature to acquire it through food only.
Therefore, supplementation with it should not be overlooked. And is strongly advisable.
Above I’ve made the list of the best vitamin B12 supplements out there for 2019. Use that to your advantage, and I’ll meet you in another article.
Other than that, all comments are warmly welcome, even one line will be truly and sincerely appreciated.
Cheers, And Have An Awesome Day, Everyone!
This article was last updated on the 26th of January 2019.